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Echemi Chemical 5-Aminosalicylic acid Description
5-Aminosalicylic acid acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.
Echemi Chemical 5-Aminosalicylic acid Basic Attributes
Molecular Formula ：C7H7NO3
Molecular Mass ：153.14
Exact Mass ：153.042587
PSA ：83.6 A^2
H-bond Acceptor ：4
H-bond Donor ：3
Echemi Chemical 5-Aminosalicylic acid Characteristics
Appearance ：off-white to gray tablets
Density ：1.5±0.1 g/cm3
Melting Point ：275-280 °C (dec.)(lit.)
Flash Point ：279-281°C
Refractive Index ：1.691
Solubility ：H2O: <0.1 g/100 mL at 21 ºC;soluble in dimethyl sulfoxide.
Storage Condition ：2-8°C
Vapor Pressure ：6.10X10-8 mm Hg at 25 deg C (est)
Stability ：Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Echemi Chemical 5-Aminosalicylic acid Safety Information
Hazard Class ：IRRITANT
HS Code ：2922509090
UN No. ：NONH for all modes of transport
Risk Code ：36/37/38-52/53
Safety Instructions ：26-36-24/25-61-37/39
RTECS No. ：VO1400000
Dangerous Mark ：Xi
Storage ：Warehouse ventilated, low temperature and dry
P Code ：P261-P305 + P351 + P338
Hazard Statements ：H315-H319-H335
Flammability ：Flammable; burning produces toxic nitrogen oxide fumes
Toxicity ：Peritoneal-mouse LD50: 5000 mg/kg; oral-mouse LDL0: 313 mg/kg
Toxicity Class ：moderately
Echemi Chemical 5-Aminosalicylic acid Product Usage
In manufacture of light-sensitive paper, azo and sulfur dyes. Used as an intermediate for azo and sulfur dyes, and used in the manufacture of photosensitive paper. It has a significant inhibitory effect on the inflammation of the intestinal wall; Mesalazine can inhibit the synthesis of prostaglandins that cause inflammation and the formation of leukotrienes, the inflammatory mediator. Thereby significantly inhibiting the inflammation of the intestinal mucosa. It has a better effect on the connective tissue of the inflamed intestinal wall. Used for ulcerative colitis, ulcerative proctitis and Crohn's disease.
Echemi Chemical 5-Aminosalicylic acid Material and Products
Methanesulfonyl Chloride, ZINC, Carbon Dioxide, Salicylic Acid, Zinc Acetate, 4-Aminophenol, 4-Hydroxyanilinehydrochloride, Tyramine, 3-Nitrobenzoic acid, Soda Ash, 2-Methoxyethanol, 5-(phenylazo)salicylicacid, 5-Nitrosalicylic acid, Paracetamol, Potassium Bicarbonate
Benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul, Hydroquinone, 4-Aminophenol, 5-Nitrosalicylic acid, N-ACETYL-5-AMINOSALICYLICACID, 2,5-Dihydroxybenzoicacid, ETHYL25-DIHYDROXYBENZOATE97, 5-Fluorosalicylicacid
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