Chemical Products Ganciclovir Basic Attributes

CAS No:82410-32-0
Formula:C9H13N5O4
Synonyms:GVC;HHEMG;bw-759;2'-ndg;biolf62;cymevan;bwb759u;bw-759u;rs-21592;cymevene
China Export:From 2018.11 to 2019.11, total export volume of Ganciclovir from China was 112,377,052KG while total export value was $2,146,929,254. The biggest proportion of exporting volume in the last 12 months was 9.88% in 2019.03.

Chemical Products Ganciclovir Description
Ganciclovir is a potent herpes simplex virus (HSV)inhibitor, including cytomegalovirus (CMV), with an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1).

Chemical Products Ganciclovir Basic Attributes
CAS No：82410-32-0

Molecular Formula ：C9H13N5O4

Molecular Mass ：255.23

Exact Mass ：255.096756

PSA ：135 A^2

LogP ：-1.7

EINECS ：100-001-1

InChIKeys ：IRSCQMHQWWYFCW-UHFFFAOYSA-N

H-bond Acceptor ：5

H-bond Donor ：4

RBN ：5

Chemical Products Ganciclovir Characteristics
Appearance ：white powder

Density ：1.8±0.1 g/cm3

Melting Point ：250°C

Flash Point ：9℃

Refractive Index ：1.761

Solubility ：0.1 M HCl: 10 mg/mL

Storage Condition ：2-8°C

Vapor Pressure ：4.5X10-17 mm Hg at 25 deg C (est)

Stability ：Following reconstitution with sterile water for injection, ganciclovir sodium solutions containing 50 mg of ganciclovir per ml are stable for 12 hr at 15-30 deg C and should not be refrigerated since a precipitate may form. At a concentration of 10 mg or less of ganciclovir per ml, ganciclovir sodium is physically and chemically stable in the following iv solutions 0.9% sodium chloride, 5% dextrose, Ringer's, or lactated Ringer's. Solutions containing approximately 2.5 mg of ganciclovir per ml

Chemical Products Ganciclovir Safety Information
HS Code ：2933990090

UN No. ：UN1230 - class 3 - PG 2 - Methanol, solution

WGK_Germany ：3

Risk Code ：46-60-61

Safety Instructions ：53-36/37/39-45

RTECS No. ：MF8407000

Dangerous Mark ：T

P Code ：P201-P280-P308 + P313

Hazard Statements ：H360

Toxicity ：LD50 i.p. in mice: 1-2 g/kg (Martin)

Chemical Products Ganciclovir Product Usage
1. It is used for the induction and maintenance treatment of immunodeficiency patients (including AIDS patients) complicated by cytomegalovirus retinitis. 2. It is used to prevent cytomegalovirus infection in patients receiving organ transplantation and to prevent cytomegalovirus disease in AIDS patients with positive cytomegalovirus serotest.

Chemical Products Ganciclovir Material and Products
Material ：
Guanine, Acetic acid, 2-Mercaptoethanol, Ethyl Acetate, N-[9-[[2-(Acetyloxy)-1-[(acetyloxy)methyl]ethoxy]m, Sodium sulfate, Potassium Iodide, Sodium Chloride, 1,1'-[[2-(Chloromethoxy)-1,3-propanediyl]bis(oxymethylene)]bisbe

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