The relationship between erectile dysfunction severity, mean platelet volume and vitamin D levels

by John Moses on Apr 10, 2018 Sports & Recreation 1586 Views

Erectile dysfunction (ED) is defined as the incapability to develop and/or maintain penile erection, is one of the most common sexual disorders in men. ED is related with advancing age and metabolic syndromes and several cardiovascular risk factors like diabetes mellitus, hypertension and hyperlipidemia.

Vascular ED is the most common among the organic forms of ED, and it is mostly caused by primary atherosclerosis and/or endothelial dysfunction. ED is considered as a first sign of cardiovascular diseases that can identify individuals at an augmented risk of atherosclerotic cardiac disease. Platelets, a component of human blood, play an important role in the pathophysiology of atherothrombosis. Mean platelet volume (MPV) is commonly used to predict the functional alterations and activation of platelets. MPV levels might go up in various cardiovascular diseases, peripheral artery disease, and cerebrovascular diseases. Furthermore, MPV is related to various heart conditions like smoking, obesity, hyperlipidemia, hypertension, coronary artery disease, metabolic syndrome, statin and anti-hypertensive use, atrial fibrillation and systemic inflammation, thyroid diseases, diabetes mellitus and alcohol use. Despite the recognized role of vitamin D in bone and calcium metabolism, its deficit has become more prevalent in recent years. Low 25-hydroxyvitamin D levels are also associated with an increased risk of cardiovascular diseases. It is believed that suboptimal vitamin D levels affect the risk of atherosclerotic cardiovascular disease as well as lead to the development of conditions like hypertension, diabetes, inflammation and endothelial dysfunction, which are predominant vascular risk factors. Also, low vitamin D levels may contribute to the development of ED like heart diseases by causing endothelial dysfunction, inflammation, reduced glucose homeostasis and atherosclerosis. Recently, it has been revealed that MPV and 25-hydroxyvitamin D levels are negatively connected.

The study

This study was done to assess the relationship between mean platelet volume (MPV) and vitamin D levels as per ED severity.

A retrospective review of ED patients who applied to the andrology outpatient clinic was done.

The International Erectile Function Index-Erectile Function (IIEF-EF) questionnaire was used to measure the level of erectile function.

 As per this scoring system, patients were divided into two groups.

  • IIEF score: between 17 and 25 = mild ED (Group 1)
  • IIEF score between 16 and 0 = moderate-severe ED (Group 2)

Blood samples were taken from antecubital vein and MPV and 25-hydroxyvitamin D levels were evaluated.

In total, 90 patients were included in the study. These were randomized to Group 1 (n = 41) and Group 2 (n = 49). MPV levels were significantly greater in Group 2 (p = 0.001). IIEF-EF scores and 25-hydroxyvitamin D levels were positively correlated and a negative correlation was noted between IIEF-EF scores and MPV and between 25-hydroxyvitamin D levels and MPV levels.

The verdict

Significant positive correlation between ED severity and 25-hydroxyvitamin D levels and a significant negative correlation between ED severity and MPV levels was noted.

Buy Sildenafil Citrate 100 mg from Genericviagrakart.com

Article source: https://article-realm.com/article/Sports-Recreation/171-The-relationship-between-erectile-dysfunction-severity-mean-platelet-volume-and-vitamin-D-levels.html

Reviews

Guest

Overall Rating:

Comments

No comments have been left here yet. Be the first who will do it.
Safety

captchaPlease input letters you see on the image.
Click on image to redraw.

More Author Articles

Statistics

Members
Members: 8806
Publishing
Articles: 50,573
Categories: 202
Online
Active Users: 16063
Members: 513
Guests: 15550
Bots: 163269
Visits last 24h (live): 1354
Visits last 24h (bots): 15089
Administrator, leah li, ellyse perry, Flykhalifa, Devesh Guwal, Devid Won , Raj Sanghvi, lowes emily, elynaezza, lucas, Panchmukhi Train Ambulance Services, William Smith, Extractohol, askaccountings, Aircon, Hemant Kumar, Tim Wood, martech cubejohn, Kiran Beladiya, Healthcare News, Becky Joseph, AMpuesto India, miseryclary, Grow, Maria Brooks, Mark Taylor, Becky Joseph, Abhishek Singh, EZ Aircon Servicing, faraz pathan, Vedanta Air Ambulance, Matt Easterlin, Harley Wilsom, yoona kim, Payal Rajput, Central Biohub, Mbbsinblog, Pooja Dhahiya, Pramod Kumar, Allan Dias, Veative Labs, Maxiom Law , Artoon solutions, Nueva Cash, Loans Profit, Helen Clark , Quchange trading limited, Sarah Ferguson , Eliza Dorsey, mifitness, Andy, Nitesh Prasad, Nike Tech Suit, Dinesh Kumar, Aayan Ali, Reza Nikfar, Scoop Coupons, Eric Martin, Lahore Escorts, meds4gen, Tanzeel Obaid, meds4 gen1, chase.Liu, sanya roy, Company, Jonathan Zhang, Deepak Kumar, Snushuseu, Ganesh Remedies, matthew paulson, Andrew Wilson, ran viv, Marcel, Cetas Healthcare Ltd, Helen Ruth, Snushus, Peter Perker, Donnell Dean, Akshay Sharma, Canadian Cash Solutions, Integrative Systems, Call Girls in Lucknow, Kieu Thuy Hang, Vikas Chauhan, Sdreatech Private Limited, Ashwini Sharma, poojanegi, Fly Inate, mayurikathade, Alex Brown, Stephen Mundo, xacadox, hhcasdads, Zbranek & Holt Custom Homes, Henery Smith, Factory Direct Hot Tub, martin, Call Girls in Lucknow, matthew brain, John Parker, apevape, Alexander Martin, CRIF Dun and Bradstreet, Sachin Sengar, Richard Williams, Jignesh Jariwala, Tuxedo Dental Group, james mcgill, Wealth Elite, The Multifamily Mindset, Lucy Brudo, First Editing, kirti mospa, Mohammed Yusri, Amy Parker , Indomed Educare Pvt Ltd, Aishley Smith, Zivah ElectriVa Private Limited, Vtricambi, Kalyani Badkas, informative blog, noaman bhat, Lawson Sandy, Youth Destination, srikar, Ravelmovement, Myhomecargo, Softpulse Infotech, HCF Creative Force, GreenChopper, Mohit Singh, Tanja Filipovska, Fsh furniture, Aswain Medha, merleshay, manasi raviraj bandichode, Sarah Addyson, Charis Charalampous, Tina Das, May Sanders, Quickway Infosystems, Adam Taub, Hairxtensions.co.uk, REDVision Technologies Pvt. Ltd, Alice Perera, Alzbeta Berka , Smoothe Hemp, Delta 10 Cart, Johnson Piter, Noah Radford, Artoon Solutions, devinthapa, Vape Star Usa, Maria Smith

Latest Comments

i am traying To build Backlink with you please support and join us   <a href="https://ziverdo-kit.net/”>ziverdo-kit</a>
CNC machinists work in various industries but are most commonly found working for industrial manufacturers and construction where high-quality custom cnc milling savannah parts and pieces are...
on Sep 20, 2023 about Ace Divino
Whether you're at the stadium or watching from home, the England Lionesses Puffer Jacket is your symbol of support for the lionesses who continue to inspire generations with their incredible...
With a volatile economy, corporate financial consulting is really necessary to overcome  five nights at freddy's 4
on Sep 19, 2023 View Subject
Very nice, indeed. Spinner Tools

Translate To: