What are the possible side effects of ezetimibe?

What are the possible side effects of ezetimibe?

Ezetimibe is an anti-lipid drug that can be used to treat high cholesterol disorders.

Ezetimibe exerts an antihypercholesterolemic effect by lowering the total cholesterol, "bad" (LDL) cholesterol, and triglycerides in the blood. Ezetimibe enhances the prevalence of "good" cholesterol (HDL).

Ezetimibe, the effective ingredient of Ezetimibe, minimizes the absorption of cholesterol from the intestinal tract.

Ezetimibe helps the two compounds (statins) be more efficient in reducing cholesterol synthesized by the body.

Cholesterol joins other fats and is regarded as one of the fatty substances that exist in the bloodstream. Among all cholesterol components, total cholesterol is defined to include LDL and HDL cholesterol.

LDL or "bad" cholesterol that plagues the arteries may lead to plaque buildup. Taken together, plaque formation will cause arteries to become narrower over time. Narrowing these arteries can make blood transport to important organs like the heart and brain less efficient. Denying blood supply through the vessels can result in a heart attack or a stroke.

HDL cholesterol, also known as "good" cholesterol, is the one that does not stick with bad cholesterol and does not have any effect on arteries; in contrast, it protects against heart disease.

The fats in the blood, which are known as triglycerides, are one of the main reasons for heart disease.

It is often resorted to when dietary intervention is not possible to lower cholesterol levels. On the other hand, you need to be careful with your cholesterol-lowering diet due to the medication.

Side Effects of Ezetimibe

This medication, like any other, may cause side effects, though not everyone experiences them.

The following terms indicate how frequently side effects have been reported:

• Very common (may affect more than one in ten patients).
• Common (can affect up to one in ten patients)
• Uncommon (may affect up to one in 100 patients)
• Rare (can affect up to one in every 1,000 patients).
• Very rare (up to one in every 10,000 patients, including isolated reports).

If you have unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. Muscle problems, such as breakdowns that cause kidney damage, can be serious and potentially life-threatening.

Allergic reactions, such as swelling in the face, lips, tongue, and throat, can cause breathing or swallowing difficulties and require immediate treatment.

When used alone, the following side effects were observed:

Common:

• Abdominal pain
• Diarrhea
• Flatulence
• Feeling tired.

Uncommon:

• elevations in some laboratory blood tests of the liver (transaminases) or muscle (CK) function
• Cough
• Indigestion
• Heartburn
• nausea
• joint pain
• muscle spasms
• neck pain
• decreased appetite
• chest pain
• hot flush
• high blood pressure.

The following adverse effects were also noted when combined with statins (drugs that can lower your cholesterol):

Common:

• headache
• muscle pain
• tenderness or weakness.

Uncommon:

• tingling sensation
• dry mouth
• itching
• Rash
• Hives
• back pain
• muscle weakness
• pain in the arms and legs
• unusual tiredness or weakness
• swelling, especially in the hands and feet.

In general use, the following adverse effects have been noted:

• Dizziness
• muscle aches
• liver problems
• allergic reactions, including rash and hives 
• muscle pain, tenderness, or weakness
• Muscle breakdown 
• gallstones or inflammation of the gallbladder (which may cause abdominal pain, nausea, or vomiting) 
• inflammation of the pancreas, often with severe abdominal pain. 
• constipation
• reduction in blood cell counts, which may cause bruising or bleeding (thrombocytopenia). 
• Tingling sensation 
• depression 
• unusual tiredness or weakness
• shortness of breath.

Discuss any side effects you experience with your doctor or pharmacist.

Article source: https://article-realm.com/article/Health-Fitness/60362-What-are-the-possible-side-effects-of-ezetimibe.html