Why plasma protein tests performed?

What exactly are human plasma samples? 

Human plasma comprises 90% water and 10% hormones, proteins, vitamins, minerals, and enzymes. It is the protein-rich liquid portion of human blood that carries essential nutrients and minerals to all parts of the body. Analysis of human plasma samples from patients helps diagnose different diseases and helps biomedical research find improved diagnostic tools and newer medications to treat disease conditions.

We all know that blood's constituent parts are suspended in plasma. To get high-quality study results, carefully separating plasma samples from whole blood samples is a mandatory prerequisite. Densities of various blood components vary greatly. Therefore, centrifugation is typically used to separate plasma samples from blood samples to obtain supernatant clear fluid plasma.

What are plasma protein tests and their application?

Blood tests that measure the number of proteins in the blood are known as plasma protein tests or total protein tests. It is usually done to assess the overall metabolic health of the patient. Plasma protein tests mainly estimate albumin and globulin levels in the blood. The rise or fall of these two plasma proteins can indicate different diseases. However, doctors always recommend a total protein test for the diagnosis of the following disease conditions:

• Edema or inflammation

• Kidney diseases or acute kidney injury

• Bone marrow disorders

• HIV/AIDS

• Hepatitis

• Inflammatory bowel disease

• Acute or chronic liver disease

• Malnutrition or other nutritional deficiency disorders

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